Prevaccination Antibody Confers Additional Immune Responses to Repeated Yearly Influenza Vaccination in an Elderly Population
نویسندگان
چکیده
Annual vaccination is necessary to maintain humoral immunity in the elderly population. However, factors influencing response influenza have not been completely identified. The aim of this study was explore that influenced antibody responses repeated using measures were both objective and quantitative. A total 111 volunteers aged > 61 years vaccinated subcutaneously with one dose vaccine from 2005-2006 season through 2009-2010 season. after evaluated. seroprotection rates (PRs) significantly higher responders (subjects a titer season) than nonresponders only 2006-2007 2007-2008 seasons. PRs seropositive individuals prevaccination seronegative for all three virus strains almost 5 years. Age, gender, 2004-2005 did influence response. These results suggest an immune at certain time point would predict near future. following ideal predictor future last over several
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ژورنال
عنوان ژورنال: World Journal of Vaccines
سال: 2022
ISSN: ['2160-5823', '2160-5815']
DOI: https://doi.org/10.4236/wjv.2022.122002